Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0326052
PubChem CID
Molecular Formula
C19H23N3
Molecular Weight
293.414 g/mol
Synonyms/Alias
[CHEMBL93873; SCHEMBL499289; BDBM50081748; 4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piperidine]
InChI Key
CXSBVUAWHYXWQZ-UHFFFAOYSA-N
InChI
InChI=1S/C19H23N3/c1-2-6-17(7-3-1)14-18-9-12-22(13-10-18)11-5-4-8-19-15-20-16-21-19/h1-3,6-7,15-16,1...
IUPAC Name
4-benzyl-1-[4-(1H-imidazol-5-yl)but-3-ynyl]piperidine
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

45 47 0 0 0 0 0 0 0 0999 V2000
2.1224 0.7046 1.4895 C 0 0 0 0 0 0 0 0 0 0 0 0
0.9181 1.1449 0.6267 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.2837 0.308...

Experimental Data

Activity Data

Target Ion Channel
Glutamate receptor ionotropic subunit NMDA 1 subunit 3A
Uniprot Accession Number
Function
Antagonist
Species
Homo sapiens (Human)
IC50
IC50: 53000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
−70 mV mV
Temperature
Room Temperature
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
22
Rotatable Bonds
4
logP
3.106
Complexity
89.3927
TPSA (Ų)
31.92
H-Bond Donors
1
H-Bond Acceptors
2
Ring Count
3
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